In general, anxiety disorders is one of the mental disorders that require the help of drugs such as anti-depressant drugs to control the anxiety that often arises. This is because several scientific studies have found that the deficiency and imbalance of chemical compounds in the brain was playing an important role in the emergence of this anxiety. Serotonin is one of the main chemical compounds in the brain that has functioned as a neurotransmitter and plays an important role to regulate one’s mood, diet, and sleep patterns. So the anxiety disorder in a person believed because the body lacks this compound because of the brain constantly absorption this compounds while serotonin compound production far below normal. In addition, an imbalance between serotonin, norepinephrine, and dopamine is also believed to increase a person’s risk for an anxiety disorder. So usually the use of antidepressant drugs belonging to the SSRI group is the main choice to overcome this disorder. But lately, it turns out Benadryl is also believed to provide a mild calming effect in patients with anxiety disorders. Therefore this article will discuss the mechanism of Benadryl for anxiety briefly to know its function as a mild sedative.
As we know that Benadryl is one of the common types of drugs that are sold freely in the market. In the beginning, it was marketed only in the United States and Canada, and in its development obtained approval from various food and drug surveillance bodies so that it was freely traded in various countries. Benadryl itself goes into one of the products of antihistaminic drugs containing active chemical compounds known as diphenhydramine. So, in general, this drug is used to relieve various symptoms associated with flu, fever, and cough. In addition, this drug is also used to overcome vertigo, nausea when intoxicated, and difficulty sleeping or insomnia. But today some people use Benadryl for anxiety because it has the side effects of sleepiness and tranquilizers in most people. The first way of operation believed to be practiced by this drug is by blocking H1 receptors that are histamine and it is believed that blocking of these compounds provides a calming effect that relieves anxiety. In addition, the active compound in this drug which is diphenhydramine can act as a receptor antagonist M1 or muscarinic which is believed to give anxiolytic effect as one of the effects of tranquilizers.
In addition, the main compound in Benadryl was also able to serve as one of the inhibitors of NET compounds or norepinephrine transporters. This may happen if someone uses this drug at a moderate to high dose. As indicated in the various literature it is known that NET is one form of transport that carries the norepinephrine compound which presents in the synaptic cleft to return to the presynaptic neuron. Inhibition by the major compounds present in the drug will precisely stimulate norepinephrine compounds to stimulate noradrenergic postsynaptic receptors. The stimuli that occur in these receptors are believed to increase mood, affect one’s passion, and improve memory ability. So the use of Benadryl for anxiety can indeed be tried if you want to avoid the side effects provided by antidepressant drugs.